THE HIPPO PATHWAY TERMINAL EFFECTOR TAZ/WWTR1 MEDIATES OXALIPLATIN SENSITIVITY IN P53 PROFICIENT COLON CANCER CELLS

The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells

Abstract YAP and TAZ, the Hippo pathway terminal transcriptional activators, are frequently upregulated L-Carnitine in cancers.In tumor cells, they have been mainly associated with increased tumorigenesis controlling different aspects from cell cycle regulation, stemness, or resistance to chemotherapies.In fewer cases, they have also been shown to

read more


Using Non-Destructive Testing to Determine the Correlation between Dynamic Mechanical Properties and Bonding Strength of Wood-Plastic Composite Adhesive Joints

Wood-plastic composites (WPC) have been developed into new and important wood-based composites because of their benefits for the environment, economy, and recyclability.When combined with structural adhesives, Bread Knives WPCs will have a greatly broadened application in the construction field.In this work, epoxy resin and acrylic ester were used

read more